Research interests

The Department of Human Molecular Genetics (DHMG) was officially established in February 2008, and is a part of the Institute of Molecular Biology and Biotechnology (IMBiB) at the Faculty of Biology of Adam Mickiewicz University in Poznań, Poland. At the beginning of 2013, the genomics-oriented Laboratory of High Throughput Technologies (LHTT) was established. Research of DMHG and LHTT is closely connected and concentrates on applications of integrative genomics and in silico modeling and virtual screening to prevention, diagnosis and therapy of human diseases.

New paper published: Signal Integration of IFN-I and IFN-II with TLR4 Involves Sequential Recruitment of STAT1-Complexes and NFκB to Enhance Pro-inflammatory Transcription

On the 17th of May the research article of Anna Piaszyk-Borychowska, Lajos Széles, Attila Csermely, Hsin-Chien Chiang, Joanna Wesoły, Chien-Kuo Lee, Laszlo Nagy and Hans A. R. Bluyssen was accepted and published in Frontiers in Immunology, in the special research topic STATs and IRFs in Innate Immunity: From Transcriptional Regulators to Therapeutic Targets on June 4th. The full-length article can be viewed via the link.

New review paper published: Direct Inhibition of IRF-Dependent Transcriptional Regulatory Mechanisms Associated with Disease

On the 9th of May the review article of Aleksandra Antonczyk1, Bart Krist1, Malgorzata Sajek, Agata Michalska, Anna Piaszyk-Borychowska, Martyna Plens-Galaska, Joanna Wesoly and Hans A. R. Bluyssen was accepted and published in Frontiers in Immunology, in the special research topic STATs and IRFs in Innate Immunity: From Transcriptional Regulators to Therapeutic Targets on May 24th. The full-length article can be viewed via the link.

PhD procedure opening

On 8th March 2019 our PhD candidate, Agata Michalska opened PhD procedure. She gave a presentation entitled “Characterization of a novel intracellular positive feedback loop that controls long-term responsiveness to type I and II IFN”.

You can see on the selfie how happy is Agata after the seminar  🙂 Good job!

Course in Warsaw, 18-22.02.2019

Our PhD students, Aleksandra Antończyk, Martyna Plens-Gałąska and Agata Michalska, participated in the course for researchers, who want to plan, design and/or conduct animal experiments. Lectures took place at the University of Warsaw Biological and Chemical Research Centre and were organized by Polish Laboratory Animal Science Association (PolLASA).