Publications

2024

  1. Mahdi Eskandarian Boroujeni, Natalia Lopacinska, Aleksandra Antonczyk , Katarzyna Kluzek , Joanna Wesoly , Hans AR Bluyssen. Integrative Multi-Omics Analysis of IFNγ-induced Macrophages and Atherosclerotic Plaques Reveals Macrophage-dependent STAT1-Driven Transcription in Atherosclerosis. BIORxiv 2024 preprint. doi:https://doi.org/10.1101/2024.09.06.611606; this version posted September 6, 2024.
  2. Aleksandra Antonczyk, Katarzyna Kluzek, Natalia Herbich, Bart Krist, Dorota Wronka, Anna Karlik, Lukasz Przybyl, Adam Plewinski, Joanna Wesoly, Hans A.R. Bluyssen. Identification of ALEKSIN as a novel multi-IRF inhibitor of IRF- and STAT-mediated transcription in vascular inflammation and atherosclerosis. Frontiers in Pharmacology, submitted.

2023

  1. Nowicka, H.; Sekrecka, A.; Blaszczyk, K.; Kluzek, K.; Chang, C.; Wesoly, J.; Lee, C.; Bluyssen, H.A.R. ISGF3 and STAT2/IRF9 Control Basal and IFN-Induced Transcription through Genome-Wide Binding of Phosphorylated and Unphosphorylated Complexes to Commonly ISRE Containing ISGs.
    Int. J. Mol. Sci. 2023, 24(24), 17635; https://doi.org/10.3390/ijms242417635
  2. Nowicka, H.; Sekrecka, A.; Blaszczyk, K.; Kluzek, K.; Chang, C.; Wesoly, J.; Lee, C.; Bluyssen, H.A.R. ISGF3 and STAT2/IRF9 Direct Basal and IFN-Induced Transcription through Genome-Wide Binding of Phosphorylated and Unphosphorylated Complexes to Commonly ISRE Containing ISGs. Preprints 2023, 2023101440. https://doi.org/10.20944/preprints202310.1440.v1
  3. Agata Sekrecka, Katarzyna Kluzek, Michal Sekrecki, Mahdi Eskandarian Boroujeni, Sanaz Hasani, Shota Yamauchi, Kiyonao Sada, Joanna Wesoly, Hans Bluyssen. Time-dependent recruitment of GAF, ISGF3 and IRF1 complexes shapes IFNα and IFNγ-activated transcriptional responses and explains mechanistic and functional overlap. Cell. Mol. Life Sci. 80, 187 (2023). https://doi.org/10.1007/s00018-023-04830-8
  4. Hans A. R. Bluyssen and Antonios Chatzigeorgiou. Editorial: Innate Immune Responses in Hepatic Health and Disease. EDITORIAL article, Front. Immunol. Sec. Molecular Innate Immunity. Volume 14 - 2023 | doi: 10.3389/fimmu.2023.1190405.
  5. Joanna Wesoly, Natalia Pstrąg, Kamil Derylo, Barbara Michalec-Wawiórka, Natalia Derebecka, Hanna Nowicka, Arkadiusz Kajdasz, Katarzyna Kluzek, Srebniak Małgorzata I, Marek Tchórzewski, Zbigniew Kwias, Hans Bluyssen. Structural, topological, and functional characterization of transmembrane proteins TMEM213, 207, 116, 72 and 30B provides a potential link to ccRCC etiology. Am J Cancer Res. 2023 May 15;13(5):1863-1883. PMID: 37293153; PMCID: PMC10244102. 

2022

  1. Mahdi Eskandarian Boroujeni, Agata Sekrecka, Aleksandra Antonczyk, Sanaz Hassani, Michal Sekrecki, Hanna Nowicka, Natalia Lopacinska, Arta Olya, Katarzyna Kluzek, Joanna Wesoly, Hans A R Bluyssen. Frontiers in Immunology, 13:888897; DOI: 10.3389/fimmu.2022.888897; PubMed
  2. Martyna Plens-Gałąska, Tomasz Woźniak, Joanna Wesoły and Hans AR Bluyssen.
    SINBAD: Structural, experimental and clinical characterization of STAT inhibitors and their potential applications,
    Scientific data, 9(1), pp.1-6; DOI: 10.1038/s41597-022-01243-3; PubMed
  3. Bayat, A.H., Azimi, H., Hassani Moghaddam, M., Ebrahimi, V., Fathi, M., Vakili, K., Mahmoudiasl, G.R., Forouzesh, M., Mahdi Eskandarian Boroujeni, Nariman, Z. and Abbaszadeh, H.A., 2022. COVID-19 causes neuronal degeneration and reduces neurogenesis in human hippocampus. Apoptosis, pp.1-17, DOI: 10.1007/s10495-022-01754-9; PubMed

2021

  1. Rafieh Alizadeh, Mahdi Eskandarian Boroujeni, Seyed Kamran Kamrava, Ava Modirzadeh Tehrani, Zohreh Bagher, Fatemeh Heidari, Hans A R Bluyssen, Mohammad Farhadi
    From Transcriptome to Behavior: Intranasal Injection of Late Passage Human Olfactory Stem Cells Displays Potential in a Rat Model of Parkinson's Disease
    ACS Chem Neurosci. 2021 Jun 16;12(12):2209-2217. doi: 10.1021/acschemneuro.1c00225. Epub 2021 May 28. PubMed
  2. Mahdi Eskandarian Boroujeni, Leila Simani, Hans A R Bluyssen, Hamid Reza Samadikhah, Soheila Zamanlui Benisi, Sanaz Hassani, Nader Akbari Dilmaghani, Mobina Fathi, Kimia Vakili, Gholam-Reza Mahmoudiasl , Hojjat Allah Abbaszadeh, Meysam Hassani Moghadda, Mohammad-Amin Abdollahifar, Abbas AliaghaeiInflammatory Response Leads to Neuronal Death in Human Post-Mortem Cerebral Cortex in Patients with COVID-19
    ACS Chem Neurosci. 2021 Jun 16;12(12):2143-2150. doi: 10.1021/acschemneuro.1c00111. Epub 2021 Jun 8. PubMed
  3. Arkadiusz Kajdasz, Weronika Majer, Katarzyna Kluzek, Jacek Sobkowiak, Tomasz Milecki, Natalia Derebecka, Zbigniew Kwias, Hans A.R. Bluyssen, Joanna Wesoly
    Identification of RCC Subtype-Specific microRNAs–Meta-Analysis of High-Throughput RCC Tumor microRNA Expression Data
    Cancers 2021, 13(3), 548; https://doi.org/10.3390/cancers13030548; Cancers
  4. Simorgh, S., Bagher, Z., Farhadi, M., Kamrava, S.K., Mahdi Eskandarian Boroujeni, Namjoo, Z., Hour, F.Q., Moradi, S. and Alizadeh, R., 2021. Magnetic Targeting of Human Olfactory Mucosa Stem Cells Following Intranasal Administration: a Novel Approach to Parkinson’s disease Treatment. Molecular Neurobiology, pp.1-13, DOI: 10.1007/s12035-021-02392-z; PubMed

2020

  1. Arkadiusz Kajdasz, Ewelina Warzych, Natalia Derebecka, Zofia E. Madeja, Dorota Lechniak, Joanna Wesoly and Piotr Pawlak
    Lipid Stores and Lipid Metabolism Associated Gene Expression in Porcine and Bovine Parthenogenetic Embryos Revealed by Fluorescent Staining and RNA-seq
    Int. J. Mol. Sci. 2020, 21(18), 6488; https://doi.org/10.3390/ijms21186488
  2. David Ballard, Jakub Winkler-Galicki, Joanna Wesoły
    Massive parallel sequencing in forensics: advantages, issues, technicalities and prospects
    Int J Legal Med. 2020; 134(4): 1291–1303. doi: 10.1007/s00414-020-02294-0. PubMed
  3.  Ryszard Krzyminiewski, Bernadeta Dobosz, Bart Krist, Grzegorz Schroeder, Joanna Kurczewska, Hans A R Bluyssen
    ESR Method in Monitoring of Nanoparticle Endocytosis in Cancer Cells
    Int J Mol Sci. 2020 Jun 19;21(12):E4388. doi: 10.3390/ijms21124388. PubMed
  4. Golsorkhdan SA*, Boroujeni ME*, Aliaghaei A, Abdollahifar MA, Ramezanpour A, Nejatbakhsh R, Anarkooli IJ, Barfi E, Fridoni MJ
    Methamphetamine administration impairs behavior, memory and underlying signaling pathways in the hippocampus
    FBehav Brain Res. 2020 Feb 3;379:112300. doi: 10.1016/j.bbr.2019.112300. PubMed
    * Authors contributed equally to this work
  5. Akhlaghpasand MH, Tizro M, Raoofi A, Meymand AZ, Farhadieh M, Khodagholi F, Khatmi A, Soltani R, Hoseini Y, Jahanian A, Boroujeni ME*, Aliaghaei A*
    Grafted Human Chorionic Stem Cells Restore Motor Function and Preclude Cerebellar Neurodegeneration in Rat Model of Cerebellar Ataxia
    Metabolic Brain Disease. DOI: 10.1007/s11011-020-00543-0
    * Corresponding authors

2019

  1. STATs and IRFs in innate immunity: from transcriptional regulators to therapeutical targets. eBook edited by Chien-Kuo Lee and Hans A.R. Bluyssen. Published in: Frontiers in Immunology September 2019
  2. Chien-Kuo Lee and Hans A. R. Bluyssen
    Editorial: STATs and IRFs in Innate Immunity: From Transcriptional Regulators to Therapeutic Targets
    Front. Immunol., 06 August 2019 | https://doi.org/10.3389/fimmu.2019.01829. Frontiers
  3. Matuła K, Richter Ł, Janczuk-Richter M, Nogala W, Grzeszkowiak M, Peplińska B, Jurga S, Wyroba E, Suski S, Bilski H, Silesian A, Bluyssen HAR, Derebecka N, Wesoły J, Łoś JM, Łoś M, Decewicz P, Dziewit L, Paczesny J, Hołyst R
    Phenotypic plasticity of Escherichia coli upon exposure to physical stress induced by ZnO nanorods
    Sci Rep. 2019 Jun 12;9(1):8575. doi: 10.1038/s41598-019-44727-w. PubMed
  4. Anna Piaszyk-Borychowska, Lajos Széles, Attila Csermely, Hsin-Chien Chiang, Joanna Wesoły, Chien-Kuo Lee, Laszlo Nagy and Hans A.R. Bluyssen
    Signal Integration of IFN-I and IFN-II with TLR4 involves sequential recruitment of STAT1-complexes and NFκB to enhance proinflammatory transcription
    Frontiers in Immunology. 2019 Jun 4;10:1253. doi: 10.3389/fimmu.2019.01253. eCollection 2019. PubMed
  5. Aleksandra Antonczyk*, Bart Krist*, Malgorzata Szelag, Agata Michalska, Anna Piaszyk-Borychowska, Martyna Plens-Galaska, Joanna Wesoly, Hans A.R. Bluyssen
    Direct inhibition of IRF-dependent transcriptional regulatory mechanisms associated with disease
    Frontiers in Immunology - Molecular Innate Immunity, 2019 May 24;10:1176. doi: 10.3389/fimmu.2019.01176. eCollection 2019. PubMed
    *Authors contributed equally
  6. Mahmoudi M, Bayat AH, Boroujeni ME, Abdollahifar MA, Ebrahimi V, Danyali S, Heidari MH, Aliaghaei A
    Curcumin protects purkinje neurons, ameliorates motor function and reduces cerebellar atrophy in rat model of cerebellar ataxia induced by 3-AP
    J Chem Neuroanat. 2019 Dec;102:101706. doi: 10.1016/j.jchemneu.2019.101706. PubMed

2018

  1. Koter MD, Święcicka M, Matuszkiewicz M, Pacak A, Derebecka N, Filipecki M. The miRNAome dynamics during developmental and metabolic reprogramming of tomato root infected with potato cyst nematode. Plant Sci. 2018 Mar;268:18-29. doi: 10.1016/j.plantsci.2017.12.003. PubMed

  2. Piórkowska K, Żukowski K, Połtowicz K, Nowak J, Wojtysiak D, Derebecka N, Wesoły J, Ropka-Molik K. Transcriptomic Changes in Broiler Chicken Hypothalamus during Growth and Development. Int J Genomics. 2018 Oct 14;2018:6049469. doi: 10.1155/2018/6049469. PubMed

  3. Kemmner S, Bachmann Q, Steiger S, Lorenz G, Honarpisheh M, Foresto-Neto O, Wang S, Carbajo-Lozoya J, Alt V, Schulte C, Chmielewski S, Bluyssen HAR, Heemann U, Baumann M, Lech M, Schmaderer C STAT1 regulates macrophage number and phenotype and prevents renal fibrosis after ischemia/reperfusion injury Am J Physiol Renal Physiol. 2018 Nov 7. doi: 10.1152/ajprenal.00004.2018. PubMed

  4. Martyna Plens-Galaska, Malgorzata Szelag, Aida Collado, Patrice Marques, Susana Vallejo, Mariella Ramos-González, Joanna Wesoly, Maria Jesus Sanz, Concepción Peiró, Hans A.R. Bluyssen Genome-Wide Inhibition of Pro-Atherogenic Gene Expression by Multi-STAT Targeting Compounds as a Novel Treatment Strategy of CVD Frontiers in Immunology. doi:10.3389/fimmu.2018.02141 PubMed

  5. Pstrąg N, Ziemnicka k, Bluyssen HAR, Wesoły J Thyroid cancers of follicular origin in genomic light - in depth overview of recently reported molecular marker candidates Molecular Cancer. 2018 doi.org/10.1186/s12943-018-0866-1 PubMed
  6. Michalska A, Blaszczyk K, Wesoly J, Bluyssen HA A positive feedback amplifier circuit that regulates ISG expression and controls type I and type II IFN responses
    Frontiers in Immunology. 2018; 9: 1135. Published online 2018 May 28. doi: 10.3389/fimmu.2018.01135 PubMed
  7. Ropka-Molik K , Pawlina-Tyszko K, Żukowski K, Piórkowska K, Żak G, Gurgul A, Derebecka N, Wesoły J Examining the Genetic Background of Porcine Muscle Growth and Development Based on Transcriptome and miRNAome Data Int J Mol Sci. 2018 Apr 16;19(4). pii: E1208. doi: 10.3390/ijms19041208. PubMed

2017

  1. Gorniewska AM, Kluzek K, Gackowska L, Kubiszewska I, Zdzienicka MZ, Bialkowska A
    Distinct cellular phenotype linked to defective DNA interstrand crosslink repair and homologous recombination.
    Mol Med Rep. 2017 Aug;16(2):1885-1899. doi: 10.3892/mmr.2017.6781. PubMed
  2. Pawlak M, Kikulska A, Wrzesinski T, Rausch T, Kwias Z, Wilczynski B, Benes V, Wesoly J, Wilanowski T
    Potential Protective Role of Grainyhead-like Genes in the Development of Clear Cell Renal Cell Carcinoma.
    Molecular Carcinogenesis 2017 May 23. doi: 10.1002/mc.22682. PubMed
  3. Budny B, Szczepanek-Parulska E, Zemojtel T, Szaflarski W, Rydzanicz M, Wesoly J, Handschuh L, Wolinski K, Piatek K, Niedziela M, Ziemnicka K, Figlerowicz M, Zabel M, Ruchala M
    Mutations in proteasome-related genes are associated with thyroidhemiagenesis.
    Endocrine 2017 May;56(2):279-285. doi: 10.1007/s12020-017-1287-4. PubMed
  4. Kluzek K, Srebniak MI, Majer W, Ida A, Milecki T, Huminska K, van der Helm RM, Silesian A, Wrzesinski TM, Wojciechowicz J, Beverloo BH, Kwias Z, Bluyssen HA, Wesoly J
    Genetic characterization of polish ccRCC patients: somatic mutation analysis of PBRM1, BAP1 and KDMC5, genomic SNP array analysis in tumor biopsy and preliminary results of chromosome aberrations analysis in plasma cell free DNA.
    Oncotarget 2017 Feb 15. doi: 10.18632/oncotarget.15331. PubMed

2016

  1. Bluyssen HA
    Cytokine Growth Factor Reviews     2016 Dec;32:1. doi: 10.1016/j.cytogfr.2016.10.004. Epub 2016 Oct 29. PubMed
  2. Szelag M, Piaszyk-Borychowska A, Wesoly J and Bluyssen HA.
    TARGETED INHIBITION OF STATs AND IRFs AS POTENTIALTREATMENT STRATEGY IN CARDIOVASCULAR DISEASE.
    Oncotarget 2016 Jul 26;7(30):48788-48812. doi: 10.18632/oncotarget.9195. PubMed
  3. Szelag M, Wesoly J and Bluyssen HA
    ADVANCES IN PEPTIDIC AND PEPTIDOMIMETIC-BASED APPROACHES TO INHIBIT STAT SIGNALING IN HUMAN DISEASES.
    Current Protein & Peptide Science 2016; 17(2):135-46. PubMed
  4. Blaszczyk K, Nowicka H, Kostyrko K, Antonczyk A, Wesoly J, Bluyssen HA
    THE UNIQUE ROLE OF STAT2 IN CONSTITUTIVE AND IFN-INDUCED TRANSCRIPTION AND ANTIVIRAL RESPONSES.
    Cytokine & Growth factor Reviews 2016 Jun;29:71-81. doi: 10.1016/j.cytogfr.2016.02.010. Epub 2016 Mar 18. PubMed
  5. Chmielewski S, Piaszyk-Borychowska A, Wesoły J and Bluyssen HA
    STAT1 AND IRF8 IN VASCULAR INFLAMMATION AND CARDIOVASCULAR DISEASE: Diagnostic and therapeutic potential.
    International reviews of immunology, 2016 Sep 2;35(5):434-454. doi:10.3109/08830185.2015.1087519.  PubMed

2015

  1. Majer W, Kluzek K,  Bluyssen HA, and Joanna Wesoły
    POTENTIAL APPROACHES AND RECENT ADVANCES IN BIOMARKER DISCOVERY IN CLEAR-CELL RENAL CELL CARCINOMA.
    J Cancer.  2015 6(11):1105-1113. doi:10.7150/jca.12145. PubMed
  2. Bluyssen HA
    STAT2-DIRECTED PATHOGEN RESPONSES.
    Oncotarget 2015 Oct 6;6(30):28525-6. doi: 10.18632/oncotarget.5266. PubMed
  3. Szelag M
    ALERGIE POKARMOWE I KRZYŻOWE – DLACZEGO CORAZ CZĘŚCIEJ NA NIE CHORUJEMY?
    Hylostet IGM 2015 (Online) 78(3) ISSN 1689-7730. Hylostet
  4. Szelag M
    CHOROBY RZADKIE: ZESPÓŁ SJÖGRENA.
    Hylostet IGM 2015 (Online) 80(1) ISSN 1689-7730. Hylostet
  5. Wrzesinski T,Szelag M, Cieslikowski W, Ida A, Giles R, Szumska J, Pozniak J, Kwias Z, Bluyssen HA, Wesoly J
    EXPRESSION OF PRE-SELECTED TMEM GENES AS POTENTIAL CLASSIFIERS OF CLINICALLY ADVANCED CCRCC TUMORS.
    BMC Cancer 2015 Jul 14;15:518. doi: 10.1186/s12885-015-1530-4. PubMed
  6. Kluzek K, Bluyssen HA, Wesoly J
    THE EPIGENETIC LANDSCAPE OF CLEAR-CELL RENAL CELL CARCINOMA.
    Journal of Kidney Cancer and VHL 2015 2(3): 90-104. JKCVHL
  7. Siwek M, Slawinska A, Rydzanicz M, Wesoly J, Fraszczak M, Suchocki T, Skiba J, Skiba K, Szyda J
    IDENTIFICATION OF CANDIDATE GENES AND MUTATIONS IN QTL REGIONS FOR IMMUNE RESPONSES IN CHICKEN.
    Anim Genet 2015 Jun;46(3):247-54. doi: 10.1111/age.12280. PubMed
  8. Pawlak M, Walkowska A, Mlącki M, Pistolic J, Wrzesiński T, Benes V, Jane SM,
    Wesoły J, Kompanowska-Jezierska E, Wilanowski T.
    CONSEQUENCES OF THE LOSS OF THE GRAINYHEAD-LIKE 1 GENE FOR RENAL GENE EXPRESSION, REGULATION OF BLOOD PRESSURE AND HEART RATE IN A MOUSE MODEL.
    Acta Biochim Pol. 2015;62(2):287-96. doi: 10.18388/abp.2015_1001. PubMed
  9. Szelag M, Czerwoniec A, Juszczak K, Wesoly J, Bluyssen HA
    CAVS - NOVEL IN SILICO SELECTION STRATEGY OF SPECIFIC STAT INHIBITORY COMPOUNDS.
    Journal of Computational Science. 2015 doi: 10.1016/j.jocs.2015.03.001. ScienceDirect
  10. Szeląg M
    ZGAGA A CHOROBA REFLUKSOWA PRZEŁYKU.
    Hylostet IGM 2015 (Online) 75(3) ISSN 1689-7730. Hylostet
  11. Szelag M, Urbaniak A, Bluyssen HA
    A THEORETICAL ANTIOXIDANT PHARMACOPHORE FOR NATURAL HYDROXYCINNAMIC ACIDS.
    Open Chemistry 2015 13: 17-31 10.1515/chem-2015-0001. De Gruyter
  12. Blaszczyk K, Olejnik A, Chen Y-L, Chmielewski S, Kostyrko K, Nowicka H, Ozgyin L, Wesoly J, Balint BL, Lee C-K, Bluyssen HA
    STAT2/IRF9 DIRECTS A PROLONGED ISGF3-LIKE TRANSCRIPTIONAL RESPONSE AND ANTIVIRAL ACTIVITY IN THE ABSENCE OF STAT1.
    Biochem J. Mar 2015 15;466(3):511-24. doi: 10.1042/BJ20140644. PubMed
  13. Szelag M, Czerwoniec A, Wesoly J, Bluyssen HA
    IDENTIFICATION OF STAT1 AND STAT3 SPECIFIC INHIBITORS USING COMPARATIVE VIRTUAL SCREENING AND DOCKING VALIDATION.
    PLoS One, 2015 10(2). doi: 10.1371/journal.pone.0116688. PubMed

2014

  1. Aoqui C, Chmielewski S, Scherer E, Eissler R, Sollinger D, Heid I, Braren R, Schmaderer C, Megens RT, Weber C, Heemann U, Tschöp M, Baumann M
    MICROVASCULAR DYSFUNCTION IN THE COURSE OF METABOLIC SYNDROME INDUCED BY HIGH-FAT DIET.
    Cardiovascular Diabetology 2014 13:31. doi: 10.1186/1475-2840-13-31. PubMed
  2. Bialkowska A, Koczorowska AM, Kluzek K
    [THE ROLE OF CENTROSOMES IN CELLS AND THEIR POTENTIAL CONTRIBUTION TO CARCINOGENESIS.]
    Postepy Hig Med Dosw (Online)2014  68: 1050-1068 10.5604/17322693.1119029. PubMed
  3. Chmielewski S, Olejnik A, Sikorski K, Pelisek J, Blaszczyk K, Aoqui C, Nowicka H, Zernecke A, Heemann U, Wesoly J, Baumann M, Bluyssen HA
    STAT1-DEPENDENT SIGNAL INTEGRATION BETWEEN IFNγ AND TLR4 IN VASCULAR CELLS REFLECT PRO-ATHEROGENIC RESPONSES IN HUMAN ATHEROSCLEROSIS.
    PLoS One 2014 9: e113318 10.1371/journal.pone.0113318. PubMed
  4. Kutrowska A, Szelag M
    LOW MOLECULAR WEIGHT ORGANIC ACIDS AND PEPTIDES INVOLVED IN THE LONG DISTANCE TRANSPORT OF TRACE METALS.
    Acta Physiologiae Plantarum 2014 36: 1957-1968 10.1007/s11738-014-1576-y. Springer
  5. Malcher J, Wesoly J, Bluyssen HA
    MOLECULAR PROPERTIES AND MEDICAL APPLICATIONS OF PEPTIDE NUCLEIC ACIDS.
    Mini Rev Med Chem 2014 14: 401-410. PubMed
  6. Sikorski K, Wesoly J, Bluyssen HA
    DATA MINING OF ATHEROSCLEROTIC PLAQUE TRANSCRIPTOMES PREDICTS STAT1-DEPENDENT INFLAMMATORY SIGNAL INTEGRATION IN VASCULAR DISEASE.
    Int J Mol Sci 2014 15: 14313-14331 10.3390/ijms150814313. PubMed
  7. Sollinger D, Eissler R, Lorenz S, Strand S, Chmielewski S, Aoqui C, Schmaderer C, Bluyssen H, Zicha J, Witzke O, Scherer E, Lutz J, Heemann U, Baumann M
    DAMAGE-ASSOCIATED MOLECULAR PATTERN ACTIVATED TOLL-LIKE RECEPTOR 4 SIGNALLING MODULATES BLOOD PRESSURE IN L-NAME-INDUCED HYPERTENSION.
    Cardiovasc Res 2014 101: 464-472 10.1093/cvr/cvt265. PubMed
  8. Szelag M, Czerwoniec A, Wesoly J, Bluyssen HA
    COMPARATIVE SCREENING AND VALIDATION AS A NOVEL TOOL TO IDENTIFY STAT-SPECIFIC INHIBITORS.
    Eur J Pharmacol 2014 740: 417-420 10.1016/j.ejphar.2014.05.047. PubMed
  9. Wojciechowska M, Ruczynski J, Rekowski P, Alenowicz M, Mucha P, Pieszko M, Miszka A, Dobkowski M, Bluijssen H
    SYNTHESIS AND HYBRIDIZATION STUDIES OF A NEW CPP-PNA CONJUGATE AS A POTENTIAL THERAPEUTIC AGENT IN ATHEROSCLEROSIS TREATMENT.
    Protein Pept Lett 2014 21: 672-678. PubMed
  10. Tholen S, Schmaderer C, Kusmenkov E, Chmielewski S, Förstl H, Kehl V, Heemann U, Baumann M, Grimmer T
    VARIABILITY OF COGNITIVE PERFORMANCE DURING HEMODIALYSIS: STANDARDIZATION OF COGNITIVE ASSESSMENT.
    Dement Geriatr Cogn Disord 2014 38(1-2): 31-38. PubMed
  11. Zodro E, Jaroszewski M, Ida A, Wrzesinski T, Kwias Z, Bluyssen H, Wesoly J
    FUT11 AS A POTENTIAL BIOMARKER OF CLEAR CELL RENAL CELL CARCINOMA PROGRESSION BASED ON META-ANALYSIS OF GENE EXPRESSION DATA.
    Tumour Biol 2014 35: 2607-2617 10.1007/s13277-013-1344-4. PubMed

2013

  1. Chen YL, Chen TT, Pai LM, Wesoly J, Bluyssen HA, Lee CK
    A TYPE I IFN-FLT3 LIGAND AXIS AUGMENTS PLASMACYTOID DENDRITIC CELL DEVELOPMENT FROM COMMON LYMPHOID PROGENITORS.
    J Exp Med 2013 210: 2515-2522 10.1084/jem.20130536. PubMed
  2. Rydzanicz M, Wrzesinski T, Bluyssen HA, Wesoly J
    GENOMICS AND EPIGENOMICS OF CLEAR CELL RENAL CELL CARCINOMA: RECENT DEVELOPMENTS AND POTENTIAL APPLICATIONS.
    Cancer Lett 2013 341: 111-126 10.1016/j.canlet.2013.08.006. PubMed
  3. Szelag M, Czerwoniec A, Wesoly J, Bluyssen HA
    REGULACJA EKSPRESJI GENÓW ZALEŻNA OD BIAŁEK STAT JAKO ODPOWIEDZ NA SYGNAŁY ZEWNĄTRZKOMÓRKOWE. In: Kuczera M, editor.
    Nowe trendy w naukach przyrodniczych 4. Krakow: CreativeTime. pp. 109-116 978-83-6305831-9. 2013
  4. Szelag M, Czerwoniec A, Wesoly J, Bluyssen HA
    IN SILICO SIMULATIONS OF STAT1 AND STAT3 SH2 DOMAIN INHIBITORS EXPLAINS CROSS-BINDING SPECIFICITY.
    In: Kuczera M, editor.
    Mlodzi naukowcy dla Polskiej Nauki Czesc 8. Krakow: CreativeTime. pp. 117-126 978-83-63058-22-7. 2013
  5. Szelag M, Sikorski K, Czerwoniec A, Szatkowska K, Wesoly J, Bluyssen HA
    IN SILICO SIMULATIONS OF STAT1 AND STAT3 INHIBITORS PREDICT SH2 DOMAIN CROSS-BINDING SPECIFICITY.
    Eur J Pharmacol 2013 720: 38-48 10.1016/j.ejphar.2013.10.055. PubMed
  6. Szelag M, Sikorski K, Wesoly J, Bluyssen HA
    STAT1 – KLUCZOWY CZYNNIK W PRO-MIAZDZYCOWEJ INTEGRACJI SZLAKÓW SYGNALIZACYJNYCH IFNγ I TLR4 W CHOROBACH NACZYN KRWIONOSNYCH.
    In: Kuczera M, editor.
    Nowe trendy w naukach przyrodniczych 3. Krakow: CreativeTime. pp. 119-126 978-83-63058-25-8. 2013
  7. Urbaniak A, Szelag M, Molski M
    THEORETICAL INVESTIGATION OF STEREOCHEMISTRY AND SOLVENT INFLUENCE ON ANTIOXIDANT ACTIVITY OF FERULIC ACID.
    Computational and Theoretical Chemistry 2013 1012: 33-40 10.1016/j.comptc.2013.02.018. ScienceDirect

2012

  1. Sikorski K, Chmielewski S, Olejnik A, Wesoly JZ, Heemann U, Baumann M, Bluyssen H
    STAT1 AS A CENTRAL MEDIATOR OF IFNγ AND TLR4 SIGNAL INTEGRATION IN VASCULAR DYSFUNCTION.
    JAKSTAT 2012 1: 241-249 10.4161/jkst.22469. PubMed
  2. Szelag M, Mikulski D, Molski M
    QUANTUM-CHEMICAL INVESTIGATION OF THE STRUCTURE AND THE ANTIOXIDANT PROPERTIES OF ALPHA-LIPOIC ACID AND ITS METABOLITES.
    J Mol Model 2012 18: 2907-2916 10.1007/s00894-011-1306-y. PubMed
  3. Urbaniak A, Molski M, Szelag M
    QUANTUM-CHEMICAL CALCULATIONS OF THE ANTIOXIDANT PROPERTIES OF TRANS-P-COUMARIC ACID AND TRANS-SINAPINIC ACID.
    Computational Methods in Science and Technology 2012 18: 117-128. CMST

2011

  1. Sikorski K, Chmielewski S, Przybyl L, Heemann U, Wesoly J, Baumann M, Bluyssen HA
    STAT1-MEDIATED SIGNAL INTEGRATION BETWEEN IFNγ AND LPS LEADS TO INCREASED EC AND SMC ACTIVATION AND MONOCYTE ADHESION.
    Am J Physiol Cell Physiol 2011 300: C1337-1344 10.1152/ajpcell.00276.2010. PubMed
  2. Sikorski K, Czerwoniec A, Bujnicki JM, Wesoly J, Bluyssen HA
    STAT1 AS A NOVEL THERAPEUTICAL TARGET IN PRO-ATHEROGENIC SIGNAL INTEGRATION OF IFNγ, TLR4 AND IL-6 IN VASCULAR DISEASE.
    Cytokine Growth Factor Rev 2011 22: 211-219 10.1016/j.cytogfr.2011.06.003. PubMed

2010

  1. Bluyssen HA, Rastmanesh MM, Tilburgs C, Jie K, Wesseling S, Goumans MJ, Boer P, Joles JA, Braam B
    IFN GAMMA-DEPENDENT SOCS3 EXPRESSION INHIBITS IL-6-INDUCED STAT3 PHOSPHORYLATION AND DIFFERENTIALLY AFFECTS IL-6 MEDIATED TRANSCRIPTIONAL RESPONSES IN ENDOTHELIAL CELLS.
    Am J Physiol Cell Physiol 2010 299: C354-362 10.1152/ajpcell.00513.2009. PubMed
  2. Wesoly J, Sikorski K, Lee CK, Bluyssen HA
    SUPPRESSOR OF CYTOKINE SIGNALING AND ACCELERATED ATHEROSCLEROSIS IN KIDNEY DISEASE.
    Acta Biochim Pol 2010 57: 251-260. PubMed

2009

  1. Rastmanesh MM, Braam B, Joles JA, Boer P, Bluyssen HA (2009) INCREASED SOCS EXPRESSION IN PERIPHERAL BLOOD MONONUCLEAR CELLS OF END STAGE RENAL DISEASE PATIENTS IS RELATED TO INFLAMMATION AND DIALYSIS MODALITY. Eur J Pharmacol 602: 163-167 10.1016/j.ejphar.2008.11.014.

2008

  1. Rastmanesh MM, Bluyssen HA, Joles JA, Boer P, Willekes N, Braam B (2008) INCREASED EXPRESSION OF SOCS3 IN MONOCYTES AND SOCS1 IN LYMPHOCYTES CORRELATES WITH PROGRESSIVE LOSS OF RENAL FUNCTION AND CARDIOVASCULAR RISK FACTORS IN CHRONIC KIDNEY DISEASE. Eur J Pharmacol 593: 99-104 10.1016/j.ejphar.2008.07.013.

2007

  1. de Vries-Bouwstra JK, Goekoop-Ruiterman YP, Wesoly J, Hulsmans HJ, de Craen AJ, Breedveld FC, Dijkmans BA, Allaart CF, Huizinga TW (2007) EX VIVO INTERLEUKIN 1 RECEPTOR ANTAGONIST PRODUCTION ON LIPOPOLYSACCHARIDE STIMULATION IS ASSOCIATED WITH RHEUMATOID ARTHRITIS AND WITH JOINT DAMAGE. Ann Rheum Dis 66: 1033-1037 10.1136/ard.2006.062463.
  2. Thabet MM, Wesoly J, Slagboom PE, Toes RE, Huizinga TW (2007) FCRL3 PROMOTER 169 CC HOMOZYGOSITY IS ASSOCIATED WITH SUSCEPTIBILITY TO RHEUMATOID ARTHRITIS IN DUTCH CAUCASIANS. Ann Rheum Dis 66: 803-806 10.1136/ard.2006.064949.
  3. Wesoly J, Hu X, Thabet MM, Chang M, Uh H, Allaart CF, Toes RE, Houwing-Duistermaat JJ, Begovich AB, Huizinga TW (2007) THE 620W ALLELE IS THE PTPN22 GENETIC VARIANT CONFERRING SUSCEPTIBILITY TO RA IN A DUTCH POPULATION. Rheumatology (Oxford) 46: 617-621 10.1093/rheumatology/kel381.
  4. Wesoly J, Szweykowska-Kulinska Z, Bluyssen HA (2007) STAT ACTIVATION AND DIFFERENTIAL COMPLEX FORMATION DICTATE SELECTIVITY OF INTERFERON RESPONSES. Acta Biochim Pol 54: 27-38.
  5. Wesseling S, Joles JA, van Goor H, Bluyssen HA, Kemmeren P, Holstege FC, Koomans HA, Braam B (2007) TRANSCRIPTOME-BASED IDENTIFICATION OF PRO- AND ANTIOXIDATIVE GENE EXPRESSION IN KIDNEY CORTEX OF NITRIC OXIDE-DEPLETED RATS. Physiol Genomics 28: 158-167 10.1152/physiolgenomics.00077.2006.

2006

  1. Braam B, Bluyssen HA (2006) EXPRESSION PROFILING IN CARDIOVASCULAR DISEASE USING MICROARRAYS. In: Pasterkamp G, de Kleijn DPV, editors. Cardiovascular Research: New Technologies, Methods, and Applications: Springer. pp. 3-44 10.1007/0-387-23329-6_1.
  2. Braam B, Langelaar-Makkinje M, Verkleij A, Bluyssen H, Verrips T, Koomans HA, Joles JA, Post JA (2006) ANTI-OXIDANT SENSITIVITY OF DONOR AGE-RELATED GENE EXPRESSION IN CULTURED FIBROBLASTS. Eur J Pharmacol 542: 154-161 10.1016/j.ejphar.2006.05.023.
  3. Wesoly J, Agarwal S, Sigurdsson S, Bussen W, Van Komen S, Qin J, van Steeg H, van Benthem J, Wassenaar E, Baarends WM, Ghazvini M, Tafel AA, Heath H, Galjart N, Essers J, Grootegoed JA, Arnheim N, Bezzubova O, Buerstedde JM, Sung P, Kanaar R (2006) DIFFERENTIAL CONTRIBUTIONS OF MAMMALIAN RAD54 PARALOGS TO RECOMBINATION, DNA DAMAGE REPAIR, AND MEIOSIS. Mol Cell Biol 26: 976-989 10.1128/MCB.26.3.976-989.2006.
  4. Wesoly J, Wessels JA, Guchelaar HJ, Huizinga TW (2006) GENETIC MARKERS OF TREATMENT RESPONSE IN RHEUMATOID ARTHRITIS. Curr Rheumatol Rep 8: 369-377.

2005

  1. Braam B, de Roos R, Bluyssen H, Kemmeren P, Holstege F, Joles JA, Koomans H (2005) NITRIC OXIDE-DEPENDENT AND NITRIC OXIDE-INDEPENDENT TRANSCRIPTIONAL RESPONSES TO HIGH SHEAR STRESS IN ENDOTHELIAL CELLS. Hypertension 45: 672-680 10.1161/01.HYP.0000154683.33414.94.
  2. Chon H, Bluyssen HA, Holstege FC, Koomans HA, Joles JA, Braam B (2005) GENE EXPRESSION OF ENERGY AND PROTEIN METABOLISM IN HEARTS OF HYPERTENSIVE NITRIC OXIDE- OR GSH-DEPLETED MICE. Eur J Pharmacol 513: 21-33 10.1016/j.ejphar.2005.01.054.
  3. van der Helm-van Mil AH, Wesoly JZ, Huizinga TW (2005) UNDERSTANDING THE GENETIC CONTRIBUTION TO RHEUMATOID ARTHRITIS. Curr Opin Rheumatol 17: 299-304.
  4. van Veleen L, Wesoly J, Kanaar R (2005) BIOCHEMICAL AND CELLULAR ASPECTS OF HOMOLOGOUS RECOMBINATION. IN: SIEDE W, KOW W, DOETSCH P, EDITORS. DNA damage recognition: Taylor & Francis Group, New York.
  5. Wesoly J, Toes RE, Slagboom PE, Huizinga TW (2005) RUNX1 INTRONIC SNP IS NOT ASSOCIATED WITH RHEUMATOID ARTHRITIS SUSCEPTIBILITY IN DUTCH CAUCASIANS. Rheumatology (Oxford) 44: 1196 10.1093/rheumatology/kei009.
  6. Wesoly J, van der Helm-van Mil AH, Toes RE, Chokkalingam AP, Carlton VE, Begovich AB, Huizinga TW (2005) ASSOCIATION OF THE PTPN22 C1858T SINGLE-NUCLEOTIDE POLYMORPHISM WITH RHEUMATOID ARTHRITIS PHENOTYPES IN AN INCEPTION COHORT. Arthritis Rheum 52: 2948-2950 10.1002/art.21294.
  7. Wesseling S, Ishola DA, Jr., Joles JA, Bluyssen HA, Koomans HA, Braam B (2005) RESISTANCE TO OXIDATIVE STRESS BY CHRONIC INFUSION OF ANGIOTENSIN II IN MOUSE KIDNEY IS NOT MEDIATED BY THE AT2 RECEPTOR. Am J Physiol Renal Physiol 288: F1191-1200 10.1152/ajprenal.00322.2004.
  8. Zhernakova A, Eerligh P, Barrera P, Wesoly JZ, Huizinga TW, Roep BO, Wijmenga C, Koeleman BP (2005) CTLA4 IS DIFFERENTIALLY ASSOCIATED WITH AUTOIMMUNE DISEASES IN THE DUTCH POPULATION. Hum Genet 118: 58-66 10.1007/s00439-005-0006-z.

2004

  1. Bluyssen HA, Lolkema MP, van Beest M, Boone M, Snijckers CM, Los M, Gebbink MF, Braam B, Holstege FC, Giles RH, Voest EE (2004) FIBRONECTIN IS A HYPOXIA-INDEPENDENT TARGET OF THE TUMOR SUPPRESSOR VHL. FEBS Lett 556: 137-142.
  2. Braam B, de Roos R, Dijk A, Boer P, Post JA, Kemmeren PP, Holstege FC, Bluysen HA, Koomans HA (2004) NITRIC OXIDE DONOR INDUCES TEMPORAL AND DOSE-DEPENDENT REDUCTION OF GENE EXPRESSION IN HUMAN ENDOTHELIAL CELLS. Am J Physiol Heart Circ Physiol 287: H1977-1986 10.1152/ajpheart.00323.2004.
  3. Chon H, Gaillard CA, van der Meijden BB, Dijstelbloem HM, Kraaijenhagen RJ, van Leenen D, Holstege FC, Joles JA, Bluyssen HA, Koomans HA, Braam B (2004) BROADLY ALTERED GENE EXPRESSION IN BLOOD LEUKOCYTES IN ESSENTIAL HYPERTENSION IS ABSENT DURING TREATMENT. Hypertension 43: 947-951 10.1161/01.HYP.0000123071.35142.72.
  4. Hoenderop JG, Chon H, Gkika D, Bluyssen HA, Holstege FC, St-Arnaud R, Braam B, Bindels RJ (2004) REGULATION OF GENE EXPRESSION BY DIETARY CA2+ IN KIDNEYS OF 25-HYDROXYVITAMIN D3-1 ALPHA-HYDROXYLASE KNOCKOUT MICE. Kidney Int 65: 531-539 10.1111/j.1523-1755.2004.00402.x.

2003

  1. Braam B, Bluyssen HA, Voest EE, Koomans HA (2003) GEN-EXPRESSIE ANALYSE MET BEHULP VAN MICROARRAYS: TECHNISCHE ACHTERGROND EN MEDISCHE TOEPASSINGEN. Nederlands Tijdschrift voor Geneeskunde 146: 1867-1873.
  2. Bross L, Wesoly J, Buerstedde JM, Kanaar R, Jacobs H (2003) SOMATIC HYPERMUTATION DOES NOT REQUIRE RAD54 AND RAD54B-MEDIATED HOMOLOGOUS RECOMBINATION. Eur J Immunol 33: 352-357 10.1002/immu.200310009.
  3. Jaco I, Munoz P, Goytisolo F, Wesoly J, Bailey S, Taccioli G, Blasco MA (2003) ROLE OF MAMMALIAN RAD54 IN TELOMERE LENGTH MAINTENANCE. Mol Cell Biol 23: 5572-5580.
  4. Koop EA, Lopes SM, Feiken E, Bluyssen HA, van der Valk M, Voest EE, Mummery CL, Moolenaar WH, Gebbink MF (2003) RECEPTOR PROTEIN TYROSINE PHOSPHATASE MU EXPRESSION AS A MARKER FOR ENDOTHELIAL CELL HETEROGENEITY; ANALYSIS OF RPTPMU GENE EXPRESSION USING LACZ KNOCK-IN MICE. Int J Dev Biol 47: 345-354.

2002

  1. Essers J, Hendriks RW, Wesoly J, Beerens CE, Smit B, Hoeijmakers JH, Wyman C, Dronkert ML, Kanaar R (2002) ANALYSIS OF MOUSE RAD54 EXPRESSION AND ITS IMPLICATIONS FOR HOMOLOGOUS RECOMBINATION. DNA Repair (Amst) 1: 779-793.

2001

  1. Ma L, Bluyssen HA, De Raeymaeker M, Laurysens V, van der Beek N, Pavliska H, van Zonneveld AJ, Tomme P, van Es HH (2001) RAPID DETERMINATION OF ADENOVIRAL VECTOR TITERS BY QUANTITATIVE REAL-TIME PCR. J Virol Methods 93: 181-188

2000

  1. Bristow R, Bluyssen HA, de Klein A, van Gent D (2000) THE SENSING AND REPAIR OF DNA DAMAGE: ATM AND DNA-PK. In: Woodgett J, editor. Frontiers of Molecular Biology: Protein Kinases: Oxford Press, U.K.

1999

  1. Bluyssen HA, Naus NC, van Os RI, Jaspers I, Hoeijmakers JH, de Klein A (1999) HUMAN AND MOUSE HOMOLOGS OF THE SCHIZOSACCHAROMYCES POMBE RAD17+ CELL CYCLE CHECKPOINT CONTROL GENE. Genomics 55: 219-228 10.1006/geno.1998.5642

1998

  1. Bluyssen HA, van Os RI, Naus NC, Jaspers I, Hoeijmakers JH, de Klein A (1998) A HUMAN AND MOUSE HOMOLOG OF THE SCHIZOSACCHAROMYCES POMBE RAD1+ CELL CYCLE CHECKPOINT CONTROL GENE. Genomics 54: 331-337 10.1006/geno.1998.5582.

1997

  1. Lee CK, Bluyssen HA, Levy DE (1997) REGULATION OF INTERFERON-ALPHA RESPONSIVENESS BY THE DURATION OF JANUS KINASE ACTIVITY. J Biol Chem 272: 21872-21877.
  2. Bluyssen HA, Levy DE (1997) STAT2 IS A TRANSCRIPTIONAL ACTIVATOR THAT REQUIRES SEQUENCE-SPECIFIC CONTACTS PROVIDED BY STAT1 AND P48 FOR STABLE INTERACTION WITH DNA. J Biol Chem 272: 4600-4605.
  3. Bluyssen HA (1997) IFN-ALPHA. In: Delves PA, Riott I, editors. Encyclopedia of Immunology. Second Edition ed: Academic Press; 2 edition. pp. 1413-1417

1996

  1. Bluyssen HA, Durbin JE, Levy DE (1996) ISGF3 GAMMA P48, A SPECIFICITY SWITCH FOR INTERFERON ACTIVATED TRANSCRIPTION FACTORS. Cytokine Growth Factor Rev 7: 11-17.

1995

  1. Bluyssen HA, Muzaffar R, Vlieststra RJ, van der Made AC, Leung S, Stark GR, Kerr IM, Trapman J, Levy DE (1995) COMBINATORIAL ASSOCIATION AND ABUNDANCE OF COMPONENTS OF INTERFERON-STIMULATED GENE FACTOR 3 DICTATE THE SELECTIVITY OF INTERFERON RESPONSES. Proc Natl Acad Sci U S A 92: 5645-5649.
  2. Levy DE, Raz R, Durbin JE, Bluyssen HA, Muzafar R, Pisharody S (1995) CYTOPLASMIC TRANSCRIPTION FACTORS: MEDIATORS OF CYTOKINE SIGNALING. In: Doherty NS, Weichmann BM, Morgan DW, Marshall LA, editors. Inflammation: Mechanisms and Therapeutics: Birkhauser Verlag Basel.
  3. Levy DE, Raz R, Durbin JE, Bluyssen H, Muzaffar R, Pisharody S (1995) CYTOPLASMIC TRANSCRIPTION FACTORS: MEDIATORS OF CYTOKINE SIGNALING. Agents Actions Suppl 47: 79-85.
  4. Bluyssen HA, Nakamura N, Vlietstra RJ, Smit EM, Hagemeijer A, Trapman J (1995) ISOLATION, PROPERTIES AND CHROMOSOMAL LOCALIZATION OF FOUR CLOSELY LINKED HAMSTER INTERFERON-ALPHA-ENCODING GENES. Gene 158: 295-300.

1994

  1. Bluyssen HA, Vlietstra RJ, van der Made A, Trapman J (1994) THE INTERFERON-STIMULATED GENE 54 K PROMOTER CONTAINS TWO ADJACENT FUNCTIONAL INTERFERON-STIMULATED RESPONSE ELEMENTS OF DIFFERENT STRENGTH, WHICH ACT SYNERGISTICALLY FOR MAXIMAL INTERFERON-ALPHA INDUCIBILITY. Eur J Biochem 220: 395-402.
  2. Bluyssen HA, Vlietstra RJ, Faber PW, Smit EM, Hagemeijer A, Trapman J (1994) STRUCTURE, CHROMOSOME LOCALIZATION, AND REGULATION OF EXPRESSION OF THE INTERFERON-REGULATED MOUSE IFI54/IFI56 GENE FAMILY. Genomics 24: 137-148 10.1006/geno.1994.1591.